During the second phase of the Chunin Exams, Sasuke and Naruto are badly injured and unconscious. When three Sound ninjas come to kill them, Sakura puts her life on the line to protect them. With the medical ninjutsu skills she learned under Tsunade, Sakura is even more effective at keeping Naruto alive. Once again, when Naruto is critically injured by Toneri during The Last: Naruto the Movie , Sakura spends three entire days healing him. Without Sakura's impressive medical skills, Naruto wouldn't be around to save the world or achieve his dreams.
Sakura has shown fierce loyalty and dedication to Naruto throughout the series. She is his rock when he needs encouragement or support. She believes in his dream and will do anything to help him achieve it. She is defensive when others insult Naruto or his ambitions.
Sakura has routinely put Naruto's feelings before her own feelings and wants. She always attempts to make decisions that she thinks are in Naruto's best interest, such as setting him and Hinata up.
None of Naruto's other friends have done as much for him or protected him as much as Sakura. Clearly, Naruto couldn't ask for a better friend.
Sakura's strength is enough to destroy buildings or upend the earth. When used against living targets, Sakura can break bones, rupture organs, or even kill with a single strike.
Furthermore, she can send chakra throughout her entire body and improve her ability to withstand crushing blows. Another objective of Tsunade's training was to increase Sakura's available chakra supply to complete the Strength of a Hundred Seal, something that would take three years do. When the seal is released, Sakura has access to all the accumulated chakra, allowing her to perform jutsu of a greater scale than she is normally able to, and among other things, make her physical attacks even more powerful.
She can also transfer this chakra to others. Sakura has shown to be efficient in shurikenjutsu, able to accurately pin a falling Naruto to a tree with a kunai from a distance. By having Katsuyu split apart and attach itself to others, Sakura could remotely monitor many allies at once, healing them and replenishing their chakra as needed. The main purpose of Tsunade's training was to teach Sakura medical ninjutsu and thus make her a medical-nin , which demanded Sakura's refined chakra control.
As such, Sakura can heal even the most fatal of injuries. Tsunade remarks that her proficiency for healing are exceptionally rare. When dealing with an enemy with an extremely resistant body, she could combine her chakra-enhanced fists with her medical ninjutsu to heal the resulting damage, eventually killing the affected cells from over-replication.
By releasing the Strength of a Hundred Seal, Sakura can put her body in a state in which it heals itself so that she doesn't need to stop to treat herself or even be fazed by injury. In the anime, she could perform a highly difficult operation alone to regenerate a missing section of the body while using a part of individual's body as a medium by using four formula-lines to restore the missing section of the body.
If healing ninjutsu proves ineffective, Sakura can make incisions in her patients with the Chakra Scalpels to try and directly treat her patients' vital organs. She can also cure those who have been poisoned by extracting the poison from their bodies, while simultaneously repairing the damage — something which even poison-experts like Chiyo cannot do.
To ensure a complete recovery, Sakura can create an effective antidote after analysing the poison's contents, even for poisons that Sasori did not believe anyone but himself could make antidotes for. Her medical expertise extends to more standard medicine as well, enabling her to perform autopsies and examine cells with a knowledge of genetics. She was taught by Tsunade how to make fast-acting sleeping gas, and was taught by Shizune on how to concoct poisons that, when coated on weapons, could debilitate or paralyse a person with a single scratch.
In the anime, Sakura created even created her own version of Military Rations Pills, intended to have more medicinal purposes and be easier to consume. While she was still in the Academy, Sakura received consistently high test scores. It is because of her diligence in her studies that Sakura initially struggled in combat situations, for which reason she was added to Team 7 so that she could benefit from the more battle-oriented Naruto and Sasuke, while in turn, they would benefit from her large knowledge base.
Sakura's intelligence is nevertheless consistently useful, making her observational enough to guess an opponent's tactics from a brief scan of the battlefield and pick up on otherwise minor inconsistencies in conversation. Sasuke deemed her analytical skills to be superior to his Sharingan. She has excellent memory, able to quickly piece together multiple pieces of information she's previously come across in order to form a hypothesis.
In actual combat, Sakura frequently relies on misleading her opponents, either by letting them think they've outsmarted her so that they lower their guard, or letting them think they've defeated her so that they will approach her, and she can defeat them with a single punch.
Four years after the war, Sakura now pregnant accompanies her husband Sasuke on his travelling, as she refused to leave his side. When she went into labour, Sasuke brought her to one of Orochimaru's hideouts and had Karin help with the delivery. Sakura gives birth to their daughter, Sarada and returns to Konoha with her family. Afterwards, Sakura and Sasuke raised their daughter together for some time, but he left the village for a top secret mission early in her childhood, leaving her with few memories of him.
Years later at the time Naruto became Hokage, Sakura watched his inauguration with her daughter. Later, Sakura attended a Five Kage Summit with her husband, who informed the Kage about uncovering evidence of Kaguya forming a new White Zetsu Army in order to face some greater threat. Agreeing to keep this information secret and wanting to safeguard the future of their daughter and the new generation, Sasuke continues his wanderings as he tries to find more information, using his Rinnegan to inspect other dimensions.
Her daughter would ask about her father and Sakura assured Sarada that Sasuke loves her and that, when he completes his important mission, he'll come home; when these conversations go on for too long, Sakura pokes Sarada's forehead and promises to continue them some other time, which is Sasuke's usual sign of affection. In the anime, as the village began getting constant attacks from an unknown culprit, Sakura treated a Konoha Purification Plant worker who had his chakra drained in the Konoha hospital.
When the culprit behind the attacks was revealed to be Sumire Kakei , a unit was deployed to apprehend her. The rogue student unleashed Nue onto the village. While Kakashi organised the unit to defend from its attack, Sakura worked with a unit to treat the injured. Several weeks later, Sakura is about to go trip with Ino but as Sakura begins to leave, she realises that a patient's teddy bear, which she had brought home so that she could sew it, has not been picked up yet.
Sakura had promised to return the bear that day but Sarada promises that she would do it for her. Later, Sakura and Ino go to seaside cliff, where Sakura and Sasuke went on their first date. Ino asks Sakura if Sasuke had contacted her. Sakura says no, wondering what Sasuke is doing at the moment.
Later that night, Sakura arrives home and asks Sarada if she returned the teddy bear, Sarada commenting it being easy. Sarada asked Sakura how her trip went, Sakura commenting it being wonderful. Fifteen years after the war, as her graduation from the Academy approaches, Sarada starts asking Sakura about Sasuke with greater earnest. Sakura struggles to answer questions about Sasuke's childhood in order to hide his past from Sarada, leading Sarada to question if Sasuke and Sakura are even married.
This upsets Sakura and she punches the ground, which then inadvertently destroys their house. Sakura faints at the realisation of what she's done. She later wakes up to find herself in the care of Shizune , who informs her that Sarada has left the village to look for Sasuke and also tells her about Sarada's doubts on her parentage.
After chuckling at her daughter's recklessness, Sakura goes after her. Sakura arrives in time to save Sasuke and Sarada from Shin Uchiha , rupturing his organs. Sakura starts apologising to Sarada for not being more open with her, but Sasuke insists that he's to blame. They are cut off by the appearance of one of Shin's creatures, which teleports him, one of his injured "sons", and Sakura to his hideout. Shin asks her to transplant organs from the son into him, which she refuses both because he's an enemy and because his son is only a child.
Shin performs the operation himself, explaining to Sakura while he does so that his sons are really his clones, and thus deserve no special consideration. Sakura is disgusted by Shin's philosophy on genetics and offspring, declaring he has no idea what it's like to be a real parent. When Shin completes his surgery, Sakura, having revealed she was pretending to be a helpless hostage to get information on Shin for Sasuke, begins attacking him, though she is overwhelmed and stabbed by scalpels.
Sasuke and the others arrive to help shortly after the fight starts and Sasuke removes some of the scalpels that Shin stabbed Sakura with. Happy to see her husband, Sakura thanks Sasuke. Shin's clones, meanwhile, kill Shin because of how he's mistreated them. He has a powerful living sword called the Samehada that can sap the chakra of its victims. Kisame himself resembles a shark-man and can transform into a hulking shark-beast that can propel itself forward at great speeds with water jets.
Furthermore, he can flood entire arenas with water and has the debilitating Water Prison Jutsu. Despite all of this, Sakura Haruno is very strong by the end of Naruto: Shippuden , and she can summon Katsuyu, allowing her to go blow for blow with Kisame's most powerful techniques. But the real difference-maker is that Sakura is a great tactician. Plus, her medical ninjutsu and Byakugou will allow her great stamina to go the distance in fighting Kisame. Kakuzu is a part of the Immortal Duo from the Akatsuki, the other being Hidan.
Kakuzu is a creature that has five hearts, which allows him to artificially access all five basic Elemental Releases. He also has tendril-like blood vessels that fill his husk of a body.
This is what would give Kakuzu the advantage over Sakura. She is powerful, resilient, and determined, but Kakuzu can change and shift his tactics with ease. He can also combine elements for increased damage. Worse yet, his peculiar form makes it harder to actually deal serious damage to him. Sakura may be able to punch out one or two of his hearts, but it would take a lot out of her to even get that chance. Might Guy is a taijutsu master capable of incredible speed, and he possesses fantastic skill.
He can also release his chakra "Gates" to further increase his speed and strength to the point where it looks like Might Guy is teleporting. All of this would undoubtedly make Might Guy a very tough opponent for Sakura, but her intellect is what gives her the advantage. Sakura's strength and stamina mean she could keep Guy busy until his chakra runs out, allowing her to make the winning move. For all of Sakura's strength and durability, it's hard to win against the very desert itself.
So long as he has access to enough sand, Gaara could drown Sakura in sand dunes and rip her apart with a sandstorm. Even without the power of Shukaku within him, Gaara of the Desert still has the ability to precisely control vast amounts of sand and bring it to bear against Sakura.
She may be able to fight back for a time, but Gaara would ultimately overwhelm Sakura. Sasori was one of the members of the Akatsuki , and an S-ranked wanted criminal. Also known as Sasori of the Red Sand, he hailed from Sunagakure and gained fame during the third great ninja war.
Sasori specialized in puppeteering and the usage of toxins. Interestingly, Sasori had already fought Sakura once and lost. Although Sakura had help from Chiyo in the fight, she was not nearly as strong as she became over the following years.
Without a doubt, Sakura surpassed his skill by a mile towards the end of the series, and she can make quick work of the former sand shinobi. Famous for slaughtering his entire clan in one night, Itachi Uchiha is one of the most powerful characters in the entire series. His skill with the Sharingan is such that even the legendary Sannin can't hold a candle to him. With his Mangekyo Sharingan, Itachi is more than capable of killing almost anyone who tries crossing him. On top of that, his lethal Susano'o possesses two ethereal weapons, known as the Yata Mirror, and the Totsuka Blade.
Against someone like him, Sakura is sure to struggle.
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